A Primer Of Human Genetics Is An Introductory Textbook Designed To Give Students The Foundation They Need To Understand And Appreciate The Extraordinary Shifts In Human Genetics That Have Accompanied The Arrival Of Genomics. The Book Lays Out The Key Concepts Of Human Evolution, Quantitative Genetics, And Personalized Medicine Before Describing The Tools That Are Missing From Most Contemporary Textbooks: Genome-wide Association Studies, Whole-genome Resequencing, Gene Expression And Epigenome Profiling, And Integrative Genomics. The Final Section Provides An Up-to-date Survey Of Specific Findings In Six Major Domains Of Human Disease: Immunological, Metabolic, Cardiovascular, Cancer, Neuropsychological, And Aging Disorders. After Reading This Textbook, Not Only Will Students Be Better Equipped To Read Current Literature, They Will Gain A Sense Of The Impact That The Revolution In Genomics Has Had For Our Understanding Of The Human Condition, As Well As Of The Major Trends In Human Genetics Research. Students Are Assumed To Have A Core Understanding Of Genetics Such As Would Be Obtained In A General Genetics Class. Each Chapter Is Approximately 20 Pages Long, And Organized Under Up To Ten Sub-headings, Most Of Which Incorporate An Illustrative Figure. Chapter Summary Points Recap The Key Messages, And References Point Students To Key Reviews And Contemporary Highlights. Several Of The Chapters Contain A Single Box, Which Provides Extra Material On Topics Such As Consent And Responsible Conduct Of Research And Methylation Analysis In Biology.--publisher Description. Conceptual Foundations -- The Human Genome -- Human Evolution -- Normal Variation -- Personalized Genomics -- Genome-wide Association Studies -- Whole Genome Sequencing -- Gene Expression Profiling -- The Epigenome -- Integrative Genomics -- Immune-related Diseases -- Metabolic Diseases -- Cardiovascular Diseases -- Cancer Genetics -- Neurological And Psychological Disorders -- Genetics Of Aging. Greg Gibson, Georgia Institute Of Technology. Includes Bibliographical References And Index.

Greg Gibson

Sunderland, Massachusetts, U.S.A.: Sinauer Associates, Inc., Publishers

Sinauer Associates; Sinauer Associates, Inc., Publishers

Oxford University Press, Incorporated

Sinauer Associates, Incorporated

United States, United States of America

First Edition, PS, 2014

1st, 2014

xiii, 442 pages : 24 cm
A Primer of Human Genetics is an introductory textbook designed to give students the foundation they need to understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. The book lays out the key concepts of human evolution, quantitative genetics, and personalized medicine before describing the tools that are missing from most contemporary textbooks: genome-wide association studies, whole-genome resequencing, gene expression and epigenome profiling, and integrative genomics. The final section provides an up-to-date survey of specific findings in six major domains of human disease: immunological, metabolic, cardiovascular, cancer, neuropsychological, and aging disorders. After reading this textbook, not only will students be better equipped to read current literature, they will gain a sense of the impact that the revolution in genomics has had for our understanding of the human condition, as well as of the major trends in human genetics research. Students are assumed to have a core understanding of genetics such as would be obtained in a general genetics class. Each chapter is approximately 20 pages long, and organized under up to ten sub-headings, most of which incorporate an illustrative figure. Chapter summary points recap the key messages, and references point students to key reviews and contemporary highlights. Several of the chapters contain a single box, which provides extra material on topics such as "Consent and Responsible Conduct of Research" and "Methylation Analysis in Biology."--Publisher description
Includes bibliographical references and index
Conceptual foundations -- The human genome -- Human evolution -- Normal variation -- Personalized genomics -- Genome-wide association studies -- Whole genome sequencing -- Gene expression profiling -- The epigenome -- Integrative genomics -- Immune-related diseases -- Metabolic diseases -- Cardiovascular diseases -- Cancer genetics -- Neurological and psychological disorders -- Genetics of aging

A Primer of Human Genetics is an introductory textbook designed to give students the foundation they need to understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. The book lays out the key concepts of human evolution, quantitative genetics, and personalized medicine before describing the tools that are missing from most contemporary genome-wide association studies, whole-genome resequencing, gene expression and epigenome profiling, and integrative genomics. The final section provides an up-to-date survey of specific findings in six major domains of human immunological, metabolic, cardiovascular, cancer, neuropsychological, and aging disorders. After reading this textbook, not only will students be better equipped to read current literature, they will gain a sense of the impact that the revolution in genomics has had for our understanding of the human condition, as well as of the major trends in
human genetics research. Students are assumed to have a core understanding of genetics such as would be obtained in a general genetics class.
Each chapter is approximately 20 pages long, and organized under up to ten sub-headings, most of which incorporate an illustrative figure. Chapter summary points recap the key messages, and references point students to key reviews and contemporary highlights. Several of the chapters contain a single box, which provides extra material on topics such as "Consent and Responsible Conduct of Research" and "Methylation Analysis in Biology."
For Instructors
Instructor's Resource Library
Available to qualified adopters, the Instructor's Resource Library includes electronic versions of all of the textbook's figures, photos, and tables. All images are provided as both low- and high-resolution JPEGs, and have been formatted and optimized for excellent legibility and projection quality. In addition, a ready-to-use PowerPoint presentation of all figures and tables is provided for each chapter of the textbook.

2024-07-01